Assertion: An amino acid in polypeptide chain is not altered due to change in third base of codon.
Reason: It is due to Wobble hypothesis

Options

A. If both Assertion and Reason are true and the Reason is the correct explanation of the Assertion.
B. If both Assertion and Reason are true and the Reason is not the correct explanation of the Assertion.
C. If Assertion is true but the Reason is false.
D. If both Assertion and Reasom are false.

Answer

To solve the question regarding the assertion and reason, we will break it down step by step.

### Step 1: Understanding the Assertion
The assertion states that "An amino acid in a polypeptide chain is not altered due to a change in the third base of a codon." This means that even if the third base of a codon changes, the amino acid that is incorporated into the polypeptide chain remains the same.

### Step 2: Understanding the Reason
The reason given is "It is due to Wobble hypothesis." The Wobble hypothesis explains how the genetic code is degenerate, meaning that multiple codons can code for the same amino acid. Specifically, it suggests that the third base of a codon can vary without affecting the amino acid that is specified.

### Step 3: Connecting the Assertion and Reason
The Wobble hypothesis supports the assertion because it explains why a change in the third base of a codon does not necessarily lead to a change in the amino acid. For example, if the codon is UUU (which codes for phenylalanine) and it changes to UUC (which also codes for phenylalanine), the amino acid remains the same despite the change in the third base.

### Step 4: Evaluating the Truth of Assertion and Reason
Both the assertion and reason are true. The assertion accurately describes a phenomenon observed in protein synthesis, and the reason provides a valid explanation for this phenomenon.

### Step 5: Conclusion
Since both the assertion and reason are true, and the reason correctly explains the assertion, we conclude that the correct answer is that both the assertion and reason are true, and the reason is the correct explanation of the assertion.

### Final Answer
Both the assertion and reason are true, and the reason is the correct explanation of the assertion.

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