Explain enzyme-replacement therapy to tr...

Explain enzyme-replacement therapy to treat adenosine deaminase deficiency? Mention two disadvantages of this procedure.

Text Solution

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Adenosine deaminase deficiency in patients can be treated by enzyme replacement therapy.

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Knowledge Check

What is the permanent cure of adenosine deaminase (ADA) deficiency in children ?

A

Bone marrow transplantation

B

Enzyme replacement therapy in which functional ADA is given to patient by injection

C

Infusion of genetically engineered lymphocytes (in which functional ADA-cDNA is introduced) into the patient's blood

D

Introduction of gene isolated from the bone marrow cells which produce ADA, into the cells of the patient at early embryonic stages

Adenosine deaminase deficiency can be permanetly cured by which of the following methods ?

A

Bone marrow transplantation

B

Enzyme replacement therapy

C

Gene therapy at early embryonic stages

D

All of these

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