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How are the following formed and involve...

How are the following formed and involved in DNA packaging in a nucleus of a cell ?
(a) Histone octamer
(b) Nucleosome
(c) Chromatin

Text Solution

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(a) Histone octamer: It is a unit comprising 2 molecules each of four histones namely, `H _(2)A, H _(2)B, H _(3)` and `H_(4).` These histone molecules are positively charged and interacts with positively charged DNA to keep it associated with itself.
(b) Nucleosome : The negatively charged DNA winds around the histone octamer (positively charged) to form a nucleosome. Nucleosome act as building block for packaging the DNA into chromatin.
(c) Chromatin : It is a complex of DNA and protein. It helps in packing of DNA into the nucleus.
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