Which one of following are not the protein /peptide/amino acid derivatives

Options

A. Insulin and glucagon
B. Thyroxin and insulin
C. Somatostatin and oxytocin
D. Cortisol and testosterone

Explanation

To solve the question of which of the following are not protein, peptide, or amino acid derivatives, we will analyze each option provided in the question step by step.

### Step-by-Step Solution:

1. **Understanding Hormone Classification**:
- Hormones can be classified into four main categories:
- Amino Acid Derivatives (e.g., thyroxine, epinephrine)
- Peptide Hormones (e.g., oxytocin, vasopressin)
- Protein Hormones (e.g., insulin, glucagon)
- Steroidal Hormones (e.g., testosterone, cortisol)

2. **Analyzing Each Option**:
- **Option 1: Insulin and Glucagon**
- Both insulin and glucagon are protein hormones. Therefore, this option does not qualify as the correct answer since they are protein derivatives.

- **Option 2: Thyroxine and Insulin**
- Thyroxine is derived from the amino acid tyrosine (an amino acid derivative), and insulin is a protein hormone. Thus, this option also does not qualify as the correct answer.

- **Option 3: Somatostatin and Oxytocin**
- Both somatostatin and oxytocin are peptide hormones. Therefore, this option does not qualify as the correct answer.

- **Option 4: Cortisol and Testosterone**
- Both cortisol and testosterone are steroid hormones. They do not fall under the categories of protein, peptide, or amino acid derivatives. Thus, this option qualifies as the correct answer.

3. **Conclusion**:
- The correct answer is **Option 4: Cortisol and Testosterone**, as they are not protein, peptide, or amino acid derivatives.