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Lack of iodine in our diet which interfe...

Lack of iodine in our diet which interfere with thyroxine synthesis lead to the development of

A

toxic goitre

B

cretinism

C

simple goitre

D

thyrotoxicosis

Text Solution

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The correct Answer is:
### Step-by-Step Solution: 1. **Understanding the Role of Iodine**: Iodine is an essential mineral required for the synthesis of thyroid hormones, specifically thyroxine (T3 and T4). Without adequate iodine, the body cannot produce these hormones effectively. **Hint**: Remember that iodine is crucial for the formation of thyroid hormones. 2. **Identifying Thyroid Hormones**: The thyroid gland produces two main hormones: T3 (triiodothyronine) and T4 (thyroxine). T3 requires 3 iodine atoms, while T4 requires 4 iodine atoms for its synthesis. **Hint**: Recall the molecular structure of T3 and T4 and their iodine content. 3. **Consequences of Iodine Deficiency**: A lack of iodine leads to decreased production of T3 and T4. This deficiency can cause the thyroid gland to enlarge, resulting in a condition known as goiter. **Hint**: Think about what happens when the body lacks a necessary nutrient for hormone production. 4. **Identifying the Condition**: The specific condition that arises from iodine deficiency is called "simple goiter." This is characterized by the enlargement of the thyroid gland due to insufficient hormone production. **Hint**: Connect the dots between iodine deficiency and thyroid enlargement. 5. **Understanding Simple Goiter**: Simple goiter is often seen in regions where the soil is deficient in iodine, leading to widespread dietary deficiencies. It can be prevented by consuming iodized salt. **Hint**: Consider where this condition is most commonly found and how it can be mitigated. 6. **Excluding Other Options**: Other conditions mentioned, such as toxic goiter, cretinism, and thyrotoxicosis, are not directly caused by iodine deficiency. Toxic goiter is due to toxins in food, cretinism results from severe iodine deficiency during pregnancy, and thyrotoxicosis is related to excessive hormone production. **Hint**: Differentiate between conditions caused by iodine deficiency and those caused by other factors. ### Final Answer: The lack of iodine in our diet, which interferes with thyroxine synthesis, leads to the development of **simple goiter**.
### Step-by-Step Solution: 1. **Understanding the Role of Iodine**: Iodine is an essential mineral required for the synthesis of thyroid hormones, specifically thyroxine (T3 and T4). Without adequate iodine, the body cannot produce these hormones effectively. **Hint**: Remember that iodine is crucial for the formation of thyroid hormones. 2. **Identifying Thyroid Hormones**: The thyroid gland produces two main hormones: T3 (triiodothyronine) and T4 (thyroxine). T3 requires 3 iodine atoms, while T4 requires 4 iodine atoms for its synthesis. ...
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