A condition in adults called as Acromegaly leading to severe disfigurement of the facial bones is caused due to is due to hypersecretion of

Options

A. excess of STH
B. excess of thyroxine
C. deficiency of thyroxine
D. excess of adrenaline

Explanation

**Step-by-Step Solution:**

1. **Understanding Acromegaly**: Acromegaly is a condition that occurs in adults characterized by the enlargement of bones and tissues, particularly in the face and extremities. This condition is a result of hormonal imbalance.

2. **Identifying the Hormone**: The key hormone involved in acromegaly is the growth hormone (GH), also known as somatotropic hormone (STH). This hormone is secreted by the anterior lobe of the pituitary gland.

3. **Effects of Growth Hormone**: In adults, an excess of growth hormone leads to the abnormal growth of bones and tissues. Unlike in children, where excess growth hormone causes gigantism due to the growth plates still being open, in adults, the growth plates are fused. Therefore, the excess growth hormone causes the bones, particularly the facial bones, to enlarge, leading to disfigurement.

4. **Conclusion**: The hypersecretion of growth hormone (GH) is the primary cause of acromegaly in adults.

5. **Final Answer**: Acromegaly is caused by the hypersecretion of growth hormone (GH).

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