As per accepted concept of hormone action, if receptor molecules are removed from target organs, the target organs will

Options

A. not respond to the hormone
B. continue to respond to hormone without any difference
C. continue to respond to the homone but in the opposite way
D. continue to respond to the hormone but will require higher concentration

Explanation

To answer the question, "As per accepted concept of hormone action, if receptor molecules are removed from target organs, the target organs will," we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Hormone Action**:
- Hormones are signaling molecules that are secreted by glands directly into the bloodstream. They travel to target organs where they exert their effects.

**Hint**: Recall that hormones are produced by ductless glands and act on specific target tissues.

2. **Role of Receptors**:
- Target organs have specific receptor molecules on their cell surfaces or within their cells. These receptors are crucial for the hormone to bind and initiate a response.

**Hint**: Remember that receptors can be either extracellular (on the cell surface) or intracellular (inside the cell).

3. **Hormone-Receptor Interaction**:
- When a hormone binds to its receptor, it forms a hormone-receptor complex that triggers a biochemical response in the target cell. This can lead to various physiological changes.

**Hint**: Think about how insulin interacts with its receptor to regulate glucose levels in the body.

4. **Consequences of Removing Receptors**:
- If the receptors are removed from the target organs, the hormone will still circulate in the bloodstream but will be unable to bind to the target cells. Consequently, the target organs will not be able to respond to the hormone.

**Hint**: Consider what happens if a key cannot fit into a lock; the lock (target organ) cannot be opened (respond) without the key (receptor).

5. **Conclusion**:
- Therefore, if receptor molecules are removed from target organs, the correct conclusion is that the target organs will **not respond to the hormone**.

**Hint**: This is a direct consequence of the absence of the necessary binding sites for the hormone.

### Final Answer:
If receptor molecules are removed from target organs, the target organs will not respond to the hormone.