DNA synthesis can be specifically measured by estimating the incorporation of radio labelled

Options

A. uracil
B. adenine
C. thymidine
D. deoxyribose sugar

Explanation

To answer the question regarding DNA synthesis measurement through the incorporation of radiolabeled components, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks which component can be radiolabeled to specifically measure DNA synthesis. This implies that we need a component that is integral to the DNA structure.

**Hint**: Think about the building blocks of DNA and which specific nucleotide would be relevant for measurement.

2. **Identifying DNA Components**: DNA is composed of four nucleotides: adenine (A), thymine (T), cytosine (C), and guanine (G). Among these, thymine is unique to DNA.

**Hint**: Recall the structure of DNA and the role of each nucleotide in its synthesis.

3. **Considering Radiolabeling**: To measure DNA synthesis, we need to use a radiolabeled form of one of the nucleotides. The question suggests that we should focus on thymidine, as it contains thymine.

**Hint**: Think about how radiolabeling works and which isotopes can be used for this purpose.

4. **Choosing the Right Isotope**: The appropriate radiolabeled component for measuring DNA synthesis is tritiated thymidine. Tritiated thymidine is thymidine in which the hydrogen atoms are replaced with tritium, a radioactive isotope of hydrogen.

**Hint**: Remember that tritiated compounds can be detected using specific techniques.

5. **Detection Method**: The incorporation of tritiated thymidine can be detected using autoradiography, a technique that allows visualization of the radioactive decay and thus the incorporation of the labeled nucleotide into newly synthesized DNA.

**Hint**: Consider how autoradiography works and why it is suitable for detecting DNA synthesis.

6. **Conclusion**: Therefore, the correct answer to the question is that DNA synthesis can be specifically measured by estimating the incorporation of radiolabeled tritiated thymidine.

### Final Answer:
DNA synthesis can be specifically measured by estimating the incorporation of radiolabeled **tritiated thymidine**.