Which of the following disease is now considered nearly eradicated from India

Options

A. Smallpox
B. Polio
C. Plague
D. Kala-azar

Explanation

To determine which disease is now considered nearly eradicated from India, we will analyze each of the four options provided: smallpox, polio, plague, and kala azar.

### Step-by-Step Solution:

1. **Understanding Smallpox**:
- Smallpox is caused by the variola virus and is characterized by fever and a distinctive skin rash.
- It is highly contagious and was responsible for significant mortality in the past.
- The World Health Organization (WHO) declared smallpox eradicated in 1980 after a successful global vaccination campaign.
- In India, smallpox has been eradicated since the late 1970s.

2. **Understanding Polio**:
- Polio is caused by the poliovirus and primarily affects the nervous system, leading to paralysis.
- India has made significant progress in reducing polio cases, with the last case reported in 2011.
- However, polio is not yet considered fully eradicated, as there are still some cases reported in other parts of the world.

3. **Understanding Plague**:
- Plague is caused by the bacterium Yersinia pestis and is transmitted through fleas.
- While there have been outbreaks in India, it is not considered nearly eradicated as sporadic cases still occur.

4. **Understanding Kala Azar**:
- Kala azar is caused by the Leishmania donovani parasite and is transmitted by sandflies.
- It remains a public health issue in certain regions of India, and efforts are ongoing to control it.

### Conclusion:
Based on the analysis, **smallpox** is the disease that is now considered nearly eradicated from India.

### Final Answer:
**Smallpox**