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Anaphase Promoting Complex (APC) is a pr...

Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?

A

Chromosomes will not condense

B

Chromosomes will be fragmented

C

Chromosomes will not segregate

D

Recombination of chromosome arms will occur

Text Solution

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The correct Answer is:
C
If anaphase promoting complex is defective in a human cell, the chromosomes will not segregate during anaphase of mitosis. APC triggers the transition form metaphase to anaphase by tagging specific proteins for degradation.
Concept Enhancer Anaphase stage of mitosis is characterised by two events
(a) Splitting of centromeres and segregation of chromosomes.
(b) Movement of chromatids towards the opposite poles .
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