Brunner's glands occurin

Options

A. sub-mucosa of duodenum
B. sub-mucosa of stomach
C. mucosa or oesophagus
D. mucosa of ileum

Explanation

### Step-by-Step Solution:

1. **Understanding Brunner's Glands**: Brunner's glands are specialized glands that secrete alkaline mucus to help neutralize gastric acid and provide an optimal environment for intestinal enzymes.

2. **Identifying the Location**: These glands are specifically located in the duodenum, which is the first part of the small intestine immediately following the stomach.

3. **Analyzing the Options**:
- **Option A: Submucosa of Duodenum** - This is the correct location for Brunner's glands.
- **Option B: Submucosa of Stomach** - Brunner's glands are not found here.
- **Option C: Mucosa of Esophagus** - Brunner's glands do not occur in the esophagus.
- **Option D: Mucosa of Ileum** - Brunner's glands are not located in the ileum.

4. **Conclusion**: Based on the structure and location of Brunner's glands, the correct answer is **Option A: Submucosa of Duodenum**.