Which of the following layers in an antral follicle is acellular?

Options

A. Granulosa
B. Theca interna
C. Stroma
D. Zona pellucide

Explanation

To determine which layer in an antral follicle is acellular, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Structure of Antral Follicles**:
- Antral follicles are a stage of ovarian follicles that contain an antrum, which is a fluid-filled cavity.

2. **Identify the Layers of Antral Follicles**:
- The main layers surrounding the oocyte in an antral follicle include:
- Granulosa cells
- Theca interna
- Theca externa
- Zona pellucida

3. **Define Acellular**:
- Acellular means that a structure does not contain any cells.

4. **Analyze Each Layer**:
- **Granulosa Cells**: These are somatic cells that surround the oocyte and are involved in hormone production and support.
- **Theca Interna**: This layer consists of steroidogenic cells that produce hormones.
- **Theca Externa**: This is a connective tissue layer that supports the follicle.
- **Zona Pellucida**: This is a glycoprotein layer that surrounds the oocyte and is acellular.

5. **Identify the Acellular Layer**:
- Among the layers mentioned, the **zona pellucida** is the only layer that is acellular, as it is a glycoprotein matrix that does not contain any cells.

6. **Conclusion**:
- Therefore, the layer in an antral follicle that is acellular is the **zona pellucida**.

### Final Answer:
The acellular layer in an antral follicle is the **zona pellucida**.

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