Which of the following events is not associated with ovulation in human female?

Options

A. Decrease in oestradiol
B. Full development of Graafian follicle
C. Release of secondary oocyte
D. LH surge

Explanation

To determine which event is not associated with ovulation in human females, we can analyze the options provided in the question step by step.

### Step 1: Understand the Process of Ovulation
- Ovulation is the process where an ovum (egg) is released from the ovary. This is a critical event in the female reproductive cycle.

### Step 2: Analyze Each Option
1. **Decrease in Estradiol**: Estradiol is a form of estrogen that plays a significant role in the menstrual cycle. Its levels peak just before ovulation and then typically decrease after ovulation. Therefore, a decrease in estradiol is **not** associated with the process of ovulation itself.

2. **Full Development of the Graafian Follicle**: The Graafian follicle is the mature ovarian follicle that releases the ovum during ovulation. Therefore, this event is directly associated with ovulation.

3. **Release of Secondary Oocyte**: The secondary oocyte is what is released during ovulation. This event is inherently linked to the process of ovulation.

4. **LH Surge**: Luteinizing hormone (LH) surges just before ovulation and is responsible for triggering the release of the ovum. This event is also closely tied to ovulation.

### Step 3: Conclusion
After analyzing the options, we can conclude that the event that is **not associated** with ovulation in human females is the **decrease in estradiol**.

### Final Answer
The event that is not associated with ovulation in human females is **the decrease in estradiol**.

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