Which of the following discoveries resulted in a Nobel Prize

Options

A. Recombination of linked genes
B. Genetic engineering
C. X-rays induce sex-linked recessive lethal mutations
D. Cytoplasmic inheritance

Explanation

To determine which of the discoveries resulted in a Nobel Prize, we can analyze each option provided in the question:

1. **Recombination of Linked Genes**: This discovery was made by T.H. Morgan. While his work was significant in the field of genetics, it did not directly result in a Nobel Prize for this specific discovery.

2. **Genetic Engineering**: This field encompasses various discoveries and techniques. The first successful DNA fragmenting was performed by Herbert Boyer and Stanley Cohen. However, the term "genetic engineering" is broad, and while there have been Nobel Prizes awarded in related areas, this specific discovery does not point to a single Nobel Prize.

3. **X-ray Induced Sex-linked Recessive Lethal Mutation**: This discovery was made by H.J. Muller, who used X-rays to induce mutations. H.J. Muller was awarded the Nobel Prize in Physiology or Medicine in 1946 for his work on the effects of X-rays on genes, making this a significant discovery that resulted in a Nobel Prize.

4. **Cytoplasmic Inheritance**: This concept was first described in the plant Mirabilis jalapa, but it was not a specific discovery that led to a Nobel Prize. The work on cytoplasmic inheritance contributed to the understanding of genetics but did not directly result in a Nobel Prize.

Based on this analysis, the correct answer is:

**The discovery that resulted in a Nobel Prize is the X-ray induced sex-linked recessive lethal mutation by H.J. Muller.**