Home
Class 12
BIOLOGY
What would happen if in a gene encoding ...

What would happen if in a gene encoding a polypeptide of 50 amino acids, `25^(th)` codon (UAU) is mutated to UA A?

A

A polypeptide of 49 amino acids will be formed

B

A polypeptide of 25 amino acids will be formed

C

A polypeptide of 24 amino acids will be formed

D

Two polypeptides of 24 and 25 amino acids will be formed

Text Solution

AI Generated Solution

The correct Answer is:
### Step-by-Step Solution: 1. **Understanding the Codon Mutation**: The original codon at the 25th position is UAU, which codes for the amino acid Tyrosine. The mutated codon is UAA, which is a stop codon. 2. **Identifying the Role of Stop Codons**: Stop codons (UAA, UAG, UGA) do not code for any amino acid. Instead, they signal the termination of the translation process during protein synthesis. 3. **Analyzing the Impact of the Mutation**: - Up to the 24th amino acid, the polypeptide chain will be synthesized normally. - When the ribosome encounters the mutated UAA codon at the 25th position, it will recognize this as a stop signal. 4. **Resulting Polypeptide Length**: Because of the premature stop signal, the translation will terminate at the 24th amino acid. Therefore, the resulting polypeptide will consist of only 24 amino acids instead of the intended 50. 5. **Conclusion**: The mutation from UAU to UAA results in a truncated polypeptide chain of 24 amino acids, which may lead to loss of function or altered function of the protein, depending on its role in the organism.

### Step-by-Step Solution: 1. **Understanding the Codon Mutation**: The original codon at the 25th position is UAU, which codes for the amino acid Tyrosine. The mutated codon is UAA, which is a stop codon. 2. **Identifying the Role of Stop Codons**: Stop codons (UAA, UAG, UGA) do not code for any amino acid. Instead, they signal the termination of the translation process during protein synthesis. 3. **Analyzing the Impact of the Mutation**: - Up to the 24th amino acid, the polypeptide chain will be synthesized normally. ...
Promotional Banner

Similar Questions

Explore conceptually related problems

In a polypeptide chain of 125 amino acids, if the 25^(th) amino acid is mutated to UAA, then :-

What would happen when blood is acidic

A gene encoding for a polypeptide of 60 amino acids get mutated at 30^(th) codon UAU becoming UAA The result would be

What would happen if human blood becomes acidic ( low pH) ?

What should the nature of genetic code if there would have been 65 amino acids?

On translation , mRNA produce a polypeptide chain , which contains 50 amino acids. if 26^( th) codon of mRNA UUU mutated and changed to UUC , then the polypeptide chain will be

What would happen if histones were to be mutated and made rich in acidic amino acids such as aspertic acid and gultamic acid in place of basic amino acids such as lysine and arginine?

What would happen if histones were to be mutated and made rich in acidic amino acids such as aspertic acid and gultamic acid in place of basic amino acids such as lysine and arginine?

In the following schematic diagram for the preparation of hydrogen gas as shown in the figure what would happen if the following changes are made? (a) In place of zinc granules , same amount of zinc dust is taken in the test tube (b) Instead of dilute sulphuric acid , dilute hydrochloric acid is taken. (c ) In place of zinc, copper turnings are taken (d) Sodium hydroxide is taken in place of dilute sulphuric acid and the tube is heated.

Assertion: An amino acid in polypeptide chain is not altered due to change in third base of codon. Reason: It is due to Wobble hypothesis