Choose the correct statement

Options

A. Nociceptors respond to changes in pressure
B. Meissner's corpuscles are thermoreceptors
C. Photoreceptors in the human eye are depolarised during darkness and become hyperpolarised in response to the light stimulus
D. Receptors do not produce graded potentials

Explanation

To solve the question "Choose the correct statement," we need to analyze the provided statements regarding different types of receptors and their functions.

### Step-by-Step Solution:

1. **Evaluate the first statement:** "Nociceptors respond to change in pressure."
- This statement is **false**. Nociceptors are specialized receptors that respond to pain, not pressure changes.

2. **Evaluate the second statement:** "Meissner's corpuscles are thermoreceptors."
- This statement is also **false**. Meissner's corpuscles are mechanoreceptors that respond to touch, not temperature.

3. **Evaluate the third statement:** "Photoreceptors in the human eye are depolarized during darkness and become hyperpolarized in response to light stimulus."
- This statement is **true**. In darkness, photoreceptors (specifically rod cells) are depolarized, and when exposed to light, they become hyperpolarized.

4. **Evaluate the fourth statement:** "Receptors do not produce graded potential."
- This statement is **false**. Receptors do produce graded potentials, which are changes in membrane potential that vary in size.

### Conclusion:
The correct statement among the options is: **"Photoreceptors in humans are depolarized during darkness and become hyperpolarized in response to light stimulus."**

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