Four healthy people in their twenties got involved in injuries resulting in damage and death of few cells of the following. Which of the cells are least likely to be replaced by new cells

Options

A. Osteocytes
B. Malpighian layer of the skin
C. Liver cells
D. Neurons

Explanation

To determine which cells are least likely to be replaced by new cells after injury, we need to understand the types of cells in the human body and their ability to regenerate. Here’s a step-by-step solution:

### Step 1: Identify the Types of Cells
Cells in the body can be classified into three main categories based on their ability to divide:
1. **Labile cells**: These cells continuously divide and regenerate (e.g., skin cells, blood cells).
2. **Stable cells**: These cells do not regularly divide but can do so when necessary (e.g., liver cells).
3. **Permanent cells**: These cells have lost the ability to divide and do not regenerate (e.g., neurons, cardiac muscle cells).

### Step 2: Analyze the Given Cells
From the question, we need to analyze the types of cells mentioned:
- **Osteocytes**: These are bone cells and are considered stable cells. They can regenerate to some extent but are not as prolific as labile cells.
- **Hepatocytes**: These are liver cells and are also stable cells. They can regenerate when needed but are not continuously dividing.
- **Neurons**: These are nerve cells and are classified as permanent cells. Once damaged, they are not replaced.
- **Cells of the Malpighian layer of the skin**: These are labile cells that continuously divide and regenerate.

### Step 3: Determine Which Cells Are Least Likely to Be Replaced
Based on the classification:
- **Neurons** are the least likely to be replaced after injury because they are permanent cells that do not undergo cell division. Once they are damaged or die, they are not replaced by new neurons.

### Conclusion
The cells least likely to be replaced by new cells after injury are **neurons**.

### Final Answer
Neurons are the cells that are least likely to be replaced by new cells after injury.

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