Which of the following have carbohydrate as prosthetic group:

Options

A. Glycoprotein
B. Chromoprotein
C. Lipoprotein
D. Nucleoprotein

Answer

To determine which of the following options has carbohydrate as a prosthetic group, we need to analyze each option provided:

1. **Glycoprotein**: Glycoproteins are proteins that have carbohydrate (sugar) molecules covalently attached to their polypeptide chains. This attachment usually occurs during post-translational modifications through a process known as glycosylation. The carbohydrate portion acts as a prosthetic group in glycoproteins, contributing to their structure and function.

2. **Chromoprotein**: Chromoproteins are proteins that contain a colored prosthetic group, typically a pigment. They do not contain carbohydrates as a prosthetic group.

3. **Lipoprotein**: Lipoproteins are complexes of lipids and proteins. The prosthetic group in lipoproteins is lipid, not carbohydrate.

4. **Nuclear Protein**: Nuclear proteins are proteins found in the nucleus of the cell and do not specifically contain carbohydrates as a prosthetic group.

Based on this analysis, the only option that contains carbohydrate as a prosthetic group is **glycoprotein**.

### Final Answer:
The correct answer is **A - glycoprotein**.