When there is change in the base sequence of DNA it is called as

Options

A. Mutagen
B. Mutation
C. Recombination
D. Translation

Answer

To answer the question "When there is a change in the base sequence of DNA, it is called as," we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Question**: The question is asking for the term that describes a change in the DNA sequence. This is a fundamental concept in genetics.

2. **Identify the Options**: The options provided are:
- A) Mutagen
- B) Mutation
- C) Recombination
- D) Translation

3. **Define Each Term**:
- **Mutagen**: These are agents (chemical, physical, or biological) that cause mutations in DNA. They do not refer to the change itself but to the cause of the change.
- **Mutation**: This term specifically refers to the change in the base sequence of DNA. It is the correct term for the alteration itself.
- **Recombination**: This refers to the process of exchanging genetic material between chromosomes during meiosis, which does not necessarily imply a change in the base sequence.
- **Translation**: This is the process of synthesizing proteins from mRNA, which is unrelated to changes in the DNA sequence.

4. **Evaluate the Options**:
- Since the question specifically asks for the change in the DNA sequence, the only term that fits this definition is "mutation."

5. **Conclusion**: The correct answer to the question is **Mutation**.

### Final Answer:
When there is a change in the base sequence of DNA, it is called **Mutation**.

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