Transformation experiment was first performed on which bacteria : -

Options

A. E. coli
B. Diplococcus pneumoniae
C. Salmonella
D. Pasteurella pestis

Answer

To answer the question "Transformation experiment was first performed on which bacteria?", we can follow these steps:

### Step 1: Understand the concept of transformation
Transformation is a process in which a bacterium takes up foreign DNA from its environment and incorporates it into its own genome. This process can lead to changes in the characteristics of the bacterium.

**Hint:** Remember that transformation is a genetic process that involves the uptake of DNA.

### Step 2: Identify key historical experiments
The transformation experiment was first described by Frederick Griffith in 1928. He conducted experiments to understand how certain bacteria could cause disease.

**Hint:** Focus on the historical context and the scientist associated with the discovery.

### Step 3: Recall the specific bacteria used by Griffith
Griffith worked with two strains of Streptococcus pneumoniae (also known as Diplococcus pneumoniae). One strain was virulent (causing disease) and the other was non-virulent (not causing disease). He found that the non-virulent strain could become virulent when mixed with heat-killed virulent bacteria.

**Hint:** Think about the specific strains of bacteria involved in Griffith's experiments.

### Step 4: Analyze the answer choices
The options given are:
A. E. coli
B. Diplococcus pneumoniae
C. Salmonella
D. Pseudomonas pestis

From our understanding, the correct answer is the bacterium that Griffith used in his transformation experiments.

**Hint:** Eliminate options that are not related to Griffith's work.

### Step 5: Conclude the answer
Based on the historical context and the specific experiments conducted by Frederick Griffith, the transformation experiment was first performed on **B. Diplococcus pneumoniae**.

**Final Answer:** B. Diplococcus pneumoniae