In which one of the following enzymes, is copper necessarily associated as an activator

Options

A. Tryptophanase
B. Lactic dehydrogenase
C. Tyrosinase
D. Carbonic anhydrase

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks which enzyme requires copper as a necessary activator. This means we need to identify an enzyme that specifically needs copper to function properly.

2. **Analyzing the Options**: The options given are:
- Tryptophanase
- Lactic dehydrogenase
- Tyrosinase
- Carbonic anhydrase

3. **Identifying the Role of Copper**:
- Tryptophanase does not require copper.
- Lactic dehydrogenase is primarily associated with NAD+ and does not require copper.
- Carbonic anhydrase uses zinc as a cofactor, not copper.
- Tyrosinase is known to require copper as a necessary activator.

4. **Function of Tyrosinase**: Tyrosinase is an enzyme involved in the production of melanin from the amino acid tyrosine. It acts as an oxidase, facilitating the oxidation of tyrosine to form melanin.

5. **Conclusion**: Based on the analysis, the enzyme that necessarily requires copper as an activator is **Tyrosinase**.

**Final Answer**: Tyrosinase

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