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Which of the statements about ''Denatura...

Which of the statements about ''Denaturation'' given below are correct ?
(a) Denaturation of proteins causes loss of secondary and tertiary structures of the protein.
(b) Denaturation leads to the conversion of double strand of DNA into single strand.
(c) Denaturation affects primary structure which gets distorted.

A

(a), (b) and (c)

B

(b) and (c)

C

(a) and (c)

D

(a) and (b)

Text Solution

AI Generated Solution

The correct Answer is:
To determine which statements about "Denaturation" are correct, let's analyze each statement one by one. ### Step 1: Analyze Statement (a) **Statement (a): Denaturation of proteins causes loss of secondary and tertiary structures of the protein.** - **Explanation:** Denaturation refers to the process where proteins lose their natural structure due to the disruption of the secondary and tertiary structures. This loss occurs because the weak interactions (like hydrogen bonds, ionic bonds, and Van der Waals forces) that maintain these structures are broken. As a result, the protein loses its biological activity. - **Conclusion:** This statement is **correct**. ### Step 2: Analyze Statement (b) **Statement (b): Denaturation leads to the conversion of double strand of DNA into single strand.** - **Explanation:** Denaturation of DNA involves the separation of the two strands of the double helix, resulting in single-stranded DNA. This process can be induced by heat or chemical agents. The temperature at which this occurs is known as the melting temperature (Tm). - **Conclusion:** This statement is **correct**. ### Step 3: Analyze Statement (c) **Statement (c): Denaturation affects primary structure which gets distorted.** - **Explanation:** The primary structure of a protein refers to the linear sequence of amino acids linked by strong covalent bonds (peptide bonds). Denaturation does not affect these covalent bonds; it primarily disrupts the weaker interactions that maintain secondary and tertiary structures. Therefore, the primary structure remains intact during denaturation. - **Conclusion:** This statement is **incorrect**. ### Final Conclusion Based on the analysis: - Statement (a) is correct. - Statement (b) is correct. - Statement (c) is incorrect. Thus, the correct answer is that statements (a) and (b) are correct.
To determine which statements about "Denaturation" are correct, let's analyze each statement one by one. ### Step 1: Analyze Statement (a) **Statement (a): Denaturation of proteins causes loss of secondary and tertiary structures of the protein.** - **Explanation:** Denaturation refers to the process where proteins lose their natural structure due to the disruption of the secondary and tertiary structures. This loss occurs because the weak interactions (like hydrogen bonds, ionic bonds, and Van der Waals forces) that maintain these structures are broken. As a result, the protein loses its biological activity. - **Conclusion:** This statement is **correct**. ...
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