Deficiency of vitamin `B_(1)` causes the disease

Options

A. Cheilosis
B. Sterility
C. Convulsions
D. Beri-Beri

Explanation

To solve the question, we need to identify the disease caused by the deficiency of vitamin B1. Here’s a step-by-step breakdown of the solution:

1. **Understand the Question**: The question asks about the disease that results from a deficiency of vitamin B1.

2. **Identify Vitamin B1**: Vitamin B1 is also known as thiamine. It plays a crucial role in carbohydrate metabolism and is essential for the proper functioning of the nervous system.

3. **Review the Options**: The options provided are:
- A) Chelosis
- B) Sterility
- C) Convulsions
- D) Beriberi

4. **Analyze Each Option**:
- **Chelosis**: This condition is typically associated with a deficiency of riboflavin (vitamin B2) and is characterized by cracks at the corners of the mouth.
- **Sterility**: This is not directly linked to vitamin B1 deficiency.
- **Convulsions**: While certain vitamin deficiencies can lead to convulsions, vitamin B1 is not specifically known for this.
- **Beriberi**: This is a disease directly associated with a deficiency of thiamine (vitamin B1). It can lead to symptoms such as weakness, weight loss, and in severe cases, paralysis and cardiac failure.

5. **Conclusion**: Based on the analysis, the correct answer is **D) Beriberi**.

### Final Answer:
The deficiency of vitamin B1 causes the disease **beriberi**.