Which hormones do stimulate the production of pancreatic juice and juice bicarbonate

Options

A. Angiotensin and epinephrine
B. Gastrin and insulin
C. Cholecystokinin and secretin
D. Insulin and glucagon

Explanation

To answer the question regarding which hormones stimulate the production of pancreatic juice and bicarbonate juice, we can break down the solution step by step.

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks for hormones that stimulate the production of pancreatic juice and bicarbonate juice.

2. **Evaluating the Options**:
- **Option A: Angiotensin and Epinephrine**: These hormones are primarily involved in regulating blood pressure and metabolic responses in the liver, not in digestion. Therefore, this option is incorrect.

- **Option B: Gastrin and Insulin**: Gastrin is involved in stimulating gastric acid secretion, while insulin primarily helps in glucose uptake. Neither of these hormones directly stimulates pancreatic juice production. Thus, this option is also incorrect.

- **Option C: Cholecystokinin (CCK) and Secretin**:
- **Cholecystokinin (CCK)** is produced in the small intestine and stimulates the secretion of pancreatic juice, which contains digestive enzymes.
- **Secretin** is also produced in the small intestine and stimulates the secretion of bicarbonate ions from the pancreas, which helps neutralize stomach acid in the small intestine.
This option is correct as both hormones are involved in the stimulation of pancreatic juice and bicarbonate secretion.

- **Option D: Insulin and Glucagon**: Insulin is involved in glucose metabolism, and glucagon has the opposite effect of insulin. Neither of these hormones is involved in stimulating pancreatic juice or bicarbonate secretion. Therefore, this option is incorrect.

3. **Conclusion**: The correct answer is **Cholecystokinin (CCK) and Secretin**, as they are the hormones responsible for stimulating the production of pancreatic juice and bicarbonate juice.

### Final Answer:
**Cholecystokinin (CCK) and Secretin** stimulate the production of pancreatic juice and bicarbonate juice.