Effect of anaesthetics on body :

Options

A. Inhibits Na–K pump
B. Kills nerves
C. Stops brain functions
D. Inactivates skin cells

Answer

### Step-by-Step Text Solution:

1. **Understanding Anesthetics**: Anesthetics are substances that induce a state of temporary loss of sensation or awareness. They are commonly used during surgical procedures to prevent pain.

2. **Mechanism of Action**: The primary mechanism by which anesthetics work is by suppressing or inhibiting voltage-gated ionic channels in the nerve membrane. These channels are crucial for the transmission of nerve impulses.

3. **Effect on Nerve Transmission**: By inhibiting these voltage-gated ionic channels, anesthetics reduce the transmission of nerve signals at synapses. This means that the signals that would normally convey pain sensations to the brain are interrupted.

4. **Role of Neurotransmitter Receptors**: Anesthetics can also affect neurotransmitter receptors at synapses. They may either inhibit or excite these receptors, further contributing to the reduction of nerve transmission.

5. **Temporary Nature of Effects**: The effects of anesthetics are generally reversible, allowing for the return of normal sensation and nerve function after the anesthetic wears off.

6. **Clinical Use**: Anesthetics are primarily used in major surgeries to prevent pain and induce sedation. Patients do not feel pain or may experience numbness during the procedure due to the action of the anesthetics.

7. **Evaluating Options**:
- **Option 1**: Inhibits NAK pump - This is correct as the NAK pump is a type of voltage-gated ionic channel.
- **Option 2**: Kills nerve - This is incorrect; anesthetics do not kill nerves.
- **Option 3**: Stops brain functioning - This is incorrect; the brain continues to function, but the person is in a sedative state.
- **Option 4**: Inactivates skin cells - This is incorrect; anesthetics do not inactivate skin cells.

8. **Conclusion**: The correct answer is **Option 1: Inhibits NAK pump**.