Exchange of bicarbonates and chloride ions between RBC and plasma is called `:-`

Options

A. Chloride shift
B. Bohr's effect
C. Haldane's effect
D. Intra cellular respiration

Answer

To solve the question regarding the exchange of bicarbonates and chloride ions between red blood cells (RBC) and plasma, we can break down the process step by step:

### Step-by-Step Solution:

1. **Understanding the Context**: The question refers to the physiological process that occurs in the body during the transport of carbon dioxide (CO2) from tissues to the lungs.

**Hint**: Think about how gases are transported in the blood and the role of red blood cells.

2. **Role of Carbonic Anhydrase**: Inside the RBCs, CO2 reacts with water (H2O) to form carbonic acid (H2CO3) with the help of the enzyme carbonic anhydrase. This reaction is crucial for the conversion of CO2 into a form that can be transported in the blood.

**Hint**: Remember the enzyme that catalyzes the reaction between CO2 and water.

3. **Dissociation of Carbonic Acid**: The carbonic acid (H2CO3) then dissociates into bicarbonate ions (HCO3-) and hydrogen ions (H+). This reaction increases the concentration of bicarbonate ions in the RBC.

**Hint**: What happens to carbonic acid when it dissociates?

4. **Bicarbonate Ion Transport**: The bicarbonate ions (HCO3-) are transported out of the RBC into the plasma. To maintain electrical neutrality within the cell, chloride ions (Cl-) move into the RBC from the plasma.

**Hint**: Consider the balance of charges as ions move in and out of the cells.

5. **Terminology**: This exchange of bicarbonate ions and chloride ions is specifically referred to as the "chloride shift." It is also known as Hamburger's phenomenon, named after the scientist who first described it.

**Hint**: What is the specific term used for this ion exchange process?

6. **Elimination of Other Options**: The other options mentioned, such as Bohr's effect and Haldane's effect, refer to different physiological phenomena related to oxygen transport and are not relevant to the exchange of bicarbonate and chloride ions.

**Hint**: Make sure to differentiate between the various physiological effects related to gas transport.

### Final Answer:
The exchange of bicarbonates and chloride ions between RBC and plasma is called the **chloride shift** (or Hamburger's phenomenon).