Give an account of Lederberg's replica plating experiment to show the genetic basis of evolution.

Explanation

The Lederberg.s Replica plating experiment : In 1952, Esther and Joshua Lederberg performed an experiment that helped to show that many mutations are random, not directed. Bacteria is grown into isolated colonies on plates and these colonies can be reproduced from an original plate to new plates by "stamping" the original plate with a cloth and then stamping empty plates with the same cloth. Bacteria from each colony are picked up on the cloth and then deposited on the new plates by the cloth. Colonies which could grow were resistant to antibiotic.
The hypothesis for the experiment is that the antibiotic resistant strains of bacteria which survived, the application of antibiotics, had the resistance before their exposure to the antibiotics, not as a result of the exposure.