Give one difference between peripheral proteins and integral proteins of the plasma membrane.

Explanation

**Step-by-Step Solution:**

1. **Definition of Integral Proteins**: Integral proteins are proteins that are permanently attached to the plasma membrane. They are embedded within the lipid bilayer and span across the membrane, which means they can extend from one side of the membrane to the other.

2. **Definition of Peripheral Proteins**: Peripheral proteins, on the other hand, are proteins that are temporarily attached to the plasma membrane. They do not penetrate the lipid bilayer but are instead located on the inner or outer surface of the membrane.

3. **Key Difference**: The key difference between integral and peripheral proteins is their attachment to the plasma membrane. Integral proteins are permanently embedded in the membrane, while peripheral proteins are only temporarily associated with the membrane.

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