State whether the following statements are true or false. The highest concentration of hydrogen ions in the mitochondria is in- the intermitochondrial space.

Answer

To determine whether the statement "The highest concentration of hydrogen ions in the mitochondria is in the intermitochondrial space" is true or false, we can follow these steps:

### Step 1: Understand the structure of mitochondria
Mitochondria have two membranes: an outer membrane and an inner membrane. The space between these membranes is called the intermembrane space, while the space inside the inner membrane is called the mitochondrial matrix.

**Hint:** Remember the different compartments of the mitochondria: outer membrane, inner membrane, intermembrane space, and mitochondrial matrix.

### Step 2: Know the role of hydrogen ions (H+)
During cellular respiration, particularly in the electron transport chain, hydrogen ions (H+) are pumped from the mitochondrial matrix into the intermembrane space. This creates a proton gradient.

**Hint:** Consider how the electron transport chain functions and where hydrogen ions are actively transported.

### Step 3: Identify where the highest concentration of H+ is located
Due to the pumping of hydrogen ions into the intermembrane space, the concentration of H+ is indeed higher in the intermembrane space compared to the mitochondrial matrix.

**Hint:** Think about the concept of concentration gradients and where ions accumulate as a result of active transport.

### Step 4: Evaluate the statement
Since the statement claims that the highest concentration of hydrogen ions is in the intermitochondrial space, and we have established that this space is actually the intermembrane space where H+ concentration is indeed higher, the statement is true.

**Hint:** Reassess the terminology used in the statement; "intermitochondrial space" may be a misnomer for "intermembrane space."

### Conclusion
The statement "The highest concentration of hydrogen ions in the mitochondria is in the intermitochondrial space" is **true**.

### Summary of Steps:
1. Understand the structure of mitochondria.
2. Know the role of hydrogen ions in cellular respiration.
3. Identify where the highest concentration of H+ is located.
4. Evaluate the statement based on the information gathered.

### Final Answer:
The statement is **true**.