Because `NAD^(+)` and FAD are critical coenzymes in cellular respiration, huge quantities must be synthesized in the cell to ensure there is no shortage.

Answer

### Step-by-Step Solution:

1. **Understanding the Coenzymes**:
- NAD⁺ (Nicotinamide Adenine Dinucleotide) and FAD (Flavin Adenine Dinucleotide) are essential coenzymes in cellular respiration.
- They play a critical role in various biochemical pathways, particularly in the production of ATP (adenosine triphosphate), which is the energy currency of the cell.

2. **Role in Cellular Respiration**:
- Both NAD⁺ and FAD are involved in the electron transport chain, which is a key component of cellular respiration. They help in the transfer of electrons, facilitating the production of ATP.

3. **Synthesis of Coenzymes**:
- The statement suggests that huge quantities of NAD⁺ and FAD must be synthesized to prevent shortages.
- However, this is not entirely accurate. While these coenzymes are important, they do not need to be synthesized in large amounts continuously.

4. **Recycling Mechanism**:
- There exists a specialized mechanism in the cell that allows for the recycling of NAD⁺ and FAD after they have participated in metabolic reactions.
- This recycling process ensures that the coenzymes can be reused multiple times, reducing the need for constant synthesis.

5. **Conclusion**:
- Given the recycling mechanism, the statement that huge quantities of NAD⁺ and FAD must be synthesized is **false**. The cell efficiently manages its coenzyme levels through recycling.

### Final Answer:
The statement is **false** because there is a mechanism for recycling NAD⁺ and FAD, eliminating the need for their continuous large-scale synthesis.

---