What chemical substances would be exchanged between the cytoplasm and the mitochondria? Indicate whether they are entering or leaving the mitochondria.

Explanation

To answer the question regarding the chemical substances exchanged between the cytoplasm and the mitochondria, we can break it down step by step:

### Step 1: Identify Substances Entering the Mitochondria
1. **Pyruvate**: This is produced during glycolysis in the cytoplasm and is transported into the mitochondria for further processing in the Krebs cycle.
2. **Oxygen (O2)**: Oxygen is essential for aerobic respiration and enters the mitochondria to be used in the electron transport chain.
3. **Reduced Hydrogen Carriers**: These include NADH and FADH2, which carry electrons to the electron transport chain.
4. **ADP (Adenosine Diphosphate)**: ADP is brought into the mitochondria to be phosphorylated to ATP.
5. **Phosphate (Pi)**: Inorganic phosphate is also transported into the mitochondria to combine with ADP to form ATP.
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