Name major forms in which `CO_2` is transported by blood.

Explanation

**Step-by-Step Text Solution:**

1. **Identify the Question**: The question asks for the major forms in which carbon dioxide (CO2) is transported by blood.

2. **List the Forms of CO2 Transport**: There are three major forms in which CO2 is transported in the blood:
- **Dissolved in Plasma**: About 5-8% of CO2 is transported in a dissolved form in the plasma.
- **Carbaminohemoglobin**: CO2 can bind with hemoglobin to form carbaminohemoglobin. This is another significant way CO2 is transported in the blood.
- **Bicarbonate Ions**: The majority of CO2 (about 70%) is transported in the form of bicarbonate ions. This process involves CO2 diffusing into red blood cells (RBCs) and being converted into carbonic acid by the enzyme carbonic anhydrase. The carbonic acid then dissociates into bicarbonate ions and hydrogen ions.
...