Suppose a calculus (stone) is blocking a major calyx, what effect might this have on capsular hydrostatic pressure (CHP) and thus on net filtration pressure (NFP)?

Explanation

To answer the question regarding the effect of a calculus (stone) blocking a major calyx on capsular hydrostatic pressure (CHP) and net filtration pressure (NFP), we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Anatomy and Function**:
- The major calyx is part of the kidney's drainage system that collects urine from the renal pelvis and channels it to the ureter.

2. **Impact of the Blockage**:
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