All enzymes get denatured at high temperature.

Answer

### Step-by-Step Solution:

1. **Understanding Enzymes**: Enzymes are biological catalysts that speed up chemical reactions in the body. Each enzyme has a specific structure that allows it to perform its function effectively.

2. **Optimum Temperature**: Every enzyme has an optimum temperature at which it functions best. This is the temperature at which the enzyme's activity is highest.

3. **Effect of High Temperature**: When the temperature exceeds the optimum level, it can lead to denaturation. Denaturation is a process where the enzyme's structure is altered, particularly the shape of the active site, which is crucial for substrate binding.

4. **Disruption of Bonds**: High temperatures can break the weak bonds (such as hydrogen bonds and ionic bonds) that maintain the enzyme's three-dimensional structure. This disruption changes the shape of the enzyme and its active site.

5. **Substrate Binding**: If the active site of the enzyme is altered, the substrate can no longer fit into the active site. This means that the enzyme cannot catalyze the reaction effectively.

6. **Conclusion**: Therefore, the statement "All enzymes get denatured at high temperature" is true because high temperatures can lead to the denaturation of enzymes, preventing them from functioning properly.