Chromosomes are visible with chromatids at one of the following phases of mitosis

Options

A. interphase
B. prophase
C. metaphase
D. anaphase

Answer

To determine at which phase of mitosis chromosomes are visible with chromatids, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Cell Cycle**: The cell cycle consists of two main phases: interphase and the mitotic phase. Mitosis is further divided into four phases: prophase, metaphase, anaphase, and telophase.

2. **Identify the Role of Chromosomes**: During mitosis, chromosomes become visible as they condense from chromatin. Each chromosome consists of two sister chromatids joined at a region called the centromere.

3. **Analyze Each Phase of Mitosis**:
- **Prophase**: Chromatin condenses into visible chromosomes, but they are still somewhat scattered and not yet aligned.
- **Metaphase**: Chromosomes align at the metaphase plate, and each chromosome is made up of two sister chromatids, making them clearly visible.
- **Anaphase**: The sister chromatids are pulled apart toward opposite poles of the cell. At this point, they are no longer considered as a single chromosome with chromatids.
- **Telophase**: Chromosomes begin to de-condense back into chromatin, and the cell prepares to divide.

4. **Conclusion**: The phase where chromosomes are clearly visible with their chromatids still attached is during **metaphase**. This is when they are aligned at the metaphase plate and can be easily observed under a microscope.

### Final Answer:
The correct answer is **metaphase**.

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