Which of the following are principal cells of areolar connective tissue and secrete maximum amount of matrix?

Options

A. Macrophage
B. Mast
C. Fibroblast
D. Histiocyte

Answer

To solve the question "Which of the following are principal cells of areolar connective tissue and secrete maximum amount of matrix?", we will analyze each option provided:

### Step-by-Step Solution:

1. **Understand Areolar Connective Tissue**: Areolar connective tissue is a type of loose connective tissue that provides support and elasticity to various organs. It contains a variety of cells and fibers.

2. **Identify the Principal Cells**: The principal cells of areolar connective tissue are responsible for synthesizing the extracellular matrix, which includes collagen and other fibers.

3. **Evaluate Each Option**:
- **Option A: Macrophage**: These are phagocytic cells that play a role in immune response. They are not primarily responsible for matrix synthesis.
- **Option B: Mast Cell**: These cells are involved in allergic reactions and release histamine. They do not synthesize the matrix.
- **Option C: Fibroblast**: Fibroblasts are the main cells in areolar connective tissue. They are responsible for producing and secreting the extracellular matrix components, including collagen fibers.
- **Option D: Astrocytes**: These are a type of glial cell found in the nervous system, not in connective tissue. They are not involved in matrix synthesis in areolar connective tissue.

4. **Conclusion**: Based on the analysis, fibroblasts (Option C) are the principal cells of areolar connective tissue and are responsible for secreting the maximum amount of matrix.

### Final Answer:
The correct answer is **Option C: Fibroblast**.

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