The proper folding of proteins following synthesis is assisted by

Options

A. Polyribosomes
B. Specific proteins called chaperons
C. Polysomes
D. Free ribosomes

Answer

**Step-by-Step Solution:**

1. **Understanding Protein Folding**: Proteins need to fold into specific three-dimensional shapes to function properly. This process occurs after the synthesis of proteins.

2. **Identifying Assistive Proteins**: The question asks about the agents that assist in the proper folding of proteins. There are several options provided: polyribosomes, specific proteins called chaperons, polysomes, and free ribosomes.

3. **Analyzing the Options**:
- **Polyribosomes**: These are clusters of ribosomes translating mRNA into proteins but do not assist in protein folding.
- **Polysomes**: Similar to polyribosomes, they are involved in translation and do not play a direct role in folding.
- **Free Ribosomes**: These ribosomes synthesize proteins in the cytoplasm but do not assist in the folding process.
- **Chaperons**: These are specific proteins known as molecular chaperones that assist in the proper folding of proteins.

4. **Understanding Chaperons**: Chaperons are crucial for the folding process. They help prevent misfolding and aggregation of newly synthesized polypeptides, ensuring that proteins achieve their correct conformation.

5. **Conclusion**: Based on the analysis, the correct answer to the question is that the proper folding of proteins following synthesis is assisted by specific proteins called chaperons.

**Final Answer**: The proper folding of proteins following synthesis is assisted by specific proteins called chaperons.

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