The chromosome morphology is best studied during

Options

A. Prophase
B. Metaphase, as the chromosomes are most condensed
C. Anaphase,as the chromosomes are most condensed
D. Telophase

Answer

To determine the phase during which chromosome morphology is best studied, we can analyze each phase of cell division:

### Step-by-Step Solution:

1. **Understanding Chromosome Morphology**: Chromosome morphology refers to the structure and appearance of chromosomes, which can be observed during cell division.

2. **Identifying the Phases of Cell Division**:
- **Prophase**: In this phase, chromosomes become visible as they start to condense. However, they are not in their most condensed form, making it difficult to study their morphology effectively.
- **Metaphase**: During metaphase, chromosomes are aligned at the cell's equatorial plane and are in a highly condensed state. This is the phase where chromosomes are best stained and observed, allowing for detailed study of their morphology.
- **Anaphase**: In anaphase, chromosomes are separated and pulled towards opposite poles of the cell. They are no longer in a condensed state, making it less suitable for studying morphology.
- **Telophase**: In telophase, chromosomes begin to de-condense back into chromatin, and the nucleolus reappears. This phase is not suitable for studying chromosome morphology as the chromosomes are not distinct.

3. **Conclusion**: The best phase to study chromosome morphology is during **metaphase**, as the chromosomes are highly condensed and can be easily stained for observation.

### Final Answer:
The chromosome morphology is best studied during **metaphase**.

---