How many ATPs are produced during the glycolysis of one molecule of glucose ?

Options

A. 4
B. 2
C. 36
D. 38

Answer

To determine how many ATPs are produced during the glycolysis of one molecule of glucose, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Glycolysis**: Glycolysis is the metabolic pathway that converts glucose into pyruvate. This process occurs in the cytoplasm of the cell and consists of a series of ten enzymatic reactions.

2. **Initial ATP Investment**: During the initial stages of glycolysis, 2 ATP molecules are consumed (used) to phosphorylate glucose and its intermediates. This is often referred to as the "investment phase" of glycolysis.

3. **ATP Production**: As glycolysis progresses, 4 ATP molecules are produced in the later stages of the pathway. This occurs through substrate-level phosphorylation.

4. **Calculating Net Gain of ATP**: To find the net gain of ATP during glycolysis, we subtract the ATP used from the ATP produced:
\[ \text{Net Gain of ATP} = \text{ATP Produced} - \text{ATP Used} = 4 - 2 = 2 \]

5. **Conclusion**: Therefore, the net gain of ATP from the glycolysis of one molecule of glucose is 2 ATP.

### Final Answer:
The number of ATPs produced during the glycolysis of one molecule of glucose is **2 ATP**.

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