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Which is true regarding rennin secretion...

Which is true regarding rennin secretion?

A

Directly proportional to the ADH levels

B

Decreased `Na^(+)` in DCT increases rennin secretion

C

Increased `K^(+)` in PCT increases renin secretion

D

Inversely proportional to the potassium levels

Text Solution

AI Generated Solution

The correct Answer is:
### Step-by-Step Solution: 1. **Understanding Renin Secretion**: Renin is an enzyme secreted by the juxtaglomerular cells located in the afferent and efferent arterioles of the kidneys. 2. **Role of Macula Densa**: The macula densa is a group of specialized cells located in the distal convoluted tubule (DCT) that is sensitive to sodium chloride (NaCl) concentration. 3. **Sodium Chloride Sensitivity**: When the concentration of sodium chloride decreases in the DCT, the macula densa detects this change. 4. **Response to Decreased Na+**: In response to lower Na+ levels, the macula densa signals the juxtaglomerular cells to increase the secretion of renin. 5. **Conclusion**: Therefore, the statement that is true regarding renin secretion is: "Decreased Na+ in DCT increases renin secretion." ### Final Answer: Decreased Na+ in DCT increases renin secretion. ---
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