Which of the following diseases is not related with hyper or hyposecretion of hormones ?

Options

A. IDDM
B. NIDDM
C. Grave's disease
D. Gull's disease

Answer

To determine which disease is not related to hyper or hyposecretion of hormones, we will analyze each option provided.

### Step-by-Step Solution:

1. **Identify the Diseases**: The question presents several diseases. We need to identify each one and understand their relation to hormone secretion.

2. **Analyze IDDM (Insulin Dependent Diabetes Mellitus)**:
- IDDM is characterized by a deficiency of insulin, which is a hormone produced by the pancreas.
- This condition arises due to the hyposecretion of insulin, leading to poor blood glucose regulation.
- **Conclusion**: IDDM is related to hyposecretion of a hormone.

3. **Analyze NIDDM (Non-Insulin Dependent Diabetes Mellitus)**:
- NIDDM, also known as Type 2 diabetes, is not directly dependent on insulin.
- It is characterized by insulin resistance and abnormal glucose metabolism, but it does not result from a direct hyper or hyposecretion of insulin.
- **Conclusion**: NIDDM is not related to hyper or hyposecretion of hormones.

4. **Analyze Graves' Disease**:
- Graves' disease is an autoimmune disorder that leads to hyperthyroidism, characterized by the overproduction of thyroid hormones.
- This condition is a result of hypersecretion of hormones from the thyroid gland.
- **Conclusion**: Graves' disease is related to hypersecretion of a hormone.

5. **Analyze Gull's Disease**:
- Gull's disease, or hypothyroidism, is characterized by insufficient production of thyroid hormones.
- This condition arises from the hyposecretion of thyroid hormones.
- **Conclusion**: Gull's disease is related to hyposecretion of a hormone.

6. **Final Conclusion**:
- After analyzing all the options, we find that NIDDM (Non-Insulin Dependent Diabetes Mellitus) is the only condition that is not directly related to hyper or hyposecretion of hormones.

### Answer:
The disease that is not related to hyper or hyposecretion of hormones is **NIDDM (Non-Insulin Dependent Diabetes Mellitus)**.

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