The effect caused by non-functioning of islets of Langerhans is

Options

A. Heart beat rate increase
B. Increased BMR
C. Hyperglycaemia
D. Tetany

Answer

### Step-by-Step Solution:

1. **Identify the Islets of Langerhans**:
- The Islets of Langerhans are clusters of cells located in the pancreas. They play a crucial role in the regulation of blood sugar levels.

2. **Understand the Function of Islets of Langerhans**:
- The primary function of the Islets of Langerhans is the production of insulin, which is secreted by the beta cells within these islets.

3. **Role of Insulin**:
- Insulin is a hormone that helps regulate blood glucose levels by facilitating the absorption of glucose into the body’s cells. This process lowers the blood sugar levels.

4. **Consequences of Non-Functioning Islets**:
- If the Islets of Langerhans are non-functioning, the body cannot produce insulin. This leads to an inability to regulate blood glucose levels effectively.

5. **Resulting Condition**:
- The lack of insulin production results in an abnormally high concentration of glucose in the blood, a condition known as hyperglycemia.

6. **Final Answer**:
- Therefore, the effect caused by the non-functioning of the Islets of Langerhans is hyperglycemia.