In the process of transport of `CO_(2)`, which phenomenon occurs between RBCs and plasma ?

Options

A. (a) Osmosis
B. (b) Adsorption
C. (c) Chloride shift
D. (d) Absorption

Answer

To answer the question regarding the phenomenon that occurs between red blood cells (RBCs) and plasma during the transport of carbon dioxide (CO₂), we can follow these steps:

### Step-by-Step Solution:

1. **Understanding CO₂ Transport**: Carbon dioxide is primarily transported in the blood in the form of bicarbonate ions (HCO₃⁻).

2. **Entry of CO₂ into RBCs**: CO₂ diffuses from the tissues into the RBCs. Inside the RBC, CO₂ combines with water (H₂O) to form carbonic acid (H₂CO₃) with the help of the enzyme carbonic anhydrase.

3. **Formation of Bicarbonate**: The carbonic acid (H₂CO₃) quickly dissociates into bicarbonate ions (HCO₃⁻) and hydrogen ions (H⁺). The bicarbonate ion is negatively charged.

4. **Bicarbonate Ion Movement**: As bicarbonate ions are formed inside the RBC, they need to be transported out into the plasma. This movement creates a higher concentration of negative charges inside the RBC compared to the plasma.

5. **Chloride Shift**: To maintain electrical neutrality, chloride ions (Cl⁻) from the plasma move into the RBCs. This exchange of bicarbonate ions moving out and chloride ions moving in is known as the **chloride shift** (or Hamburger phenomenon).

6. **Conclusion**: The phenomenon that occurs between RBCs and plasma during the transport of CO₂ is the **chloride shift**.

### Final Answer:
The correct answer is **C: Chloride Shift**.

---