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Assertion : Base analogs induce transiti...

Assertion : Base analogs induce transition.
Reason : Base analogs perform forbidden pairing.

A

a.If both Assertion and Reason are true and the Reason is the correct explanation of the Assertion, then mark (1)

B

b.If both Assertion and Reason are true ,but the Reason is not the correct explanation of the Assertion, then mark (2).

C

c.If Assertion is true, but Reason is false , then mark (3)

D

d.If both Assertion and Reason are false. , then mark (4)

Text Solution

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The correct Answer is:
### Step-by-Step Solution: 1. **Understanding Base Analogs**: - Base analogs are chemical compounds that closely resemble the structure of nucleotide bases (adenine, thymine, cytosine, and guanine) found in DNA. - Because of their similarity, they can substitute for these bases during DNA replication. **Hint**: Remember that base analogs mimic the structure of DNA bases. 2. **Induction of Transitions**: - A transition mutation is a type of point mutation where a purine is replaced by another purine (A ↔ G) or a pyrimidine is replaced by another pyrimidine (C ↔ T). - When base analogs are incorporated into DNA, they can lead to incorrect base pairing during replication, resulting in transition mutations. **Hint**: Focus on how the substitution of bases can lead to specific types of mutations. 3. **Understanding Forbidden Pairing**: - Forbidden pairing refers to the incorrect pairing of bases that occurs when base analogs are present. - For example, a base analog may pair with a base that it normally would not pair with, leading to mutations. **Hint**: Consider how base analogs disrupt normal base pairing rules. 4. **Evaluating the Assertion and Reason**: - The assertion states that base analogs induce transitions, which is true because they can cause mutations during DNA replication. - The reason states that base analogs perform forbidden pairing, which is also true as it explains how these mutations occur. **Hint**: Check if the reason logically supports the assertion. 5. **Conclusion**: - Both the assertion and the reason are true, and the reason provides a valid explanation for the assertion. Therefore, the correct answer is that both statements are true, and the reason explains the assertion. **Hint**: Look for connections between the assertion and reason to determine their relationship. ### Final Answer: Both the assertion and the reason are true, and the reason explains the assertion.
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