Malarial parasite can be obtained in RBCs of patient

Options

A. When temperature reaches normal
B. An hour before rise in temperature
C. When temperature rises with rigor
D. A few hours after temperature reaches normal

Answer

### Step-by-Step Solution

1. **Understanding the Malarial Parasite**: The malarial parasite is caused by the genus Plasmodium. It has a complex life cycle involving two hosts: the female Anopheles mosquito and humans.

2. **Life Cycle of Plasmodium**:
- In the mosquito, Plasmodium undergoes a sexual reproduction cycle and forms sporozoites.
- When a female Anopheles mosquito bites a human, these sporozoites are injected into the bloodstream.

3. **Initial Infection in Humans**:
- The sporozoites travel to the liver, where they undergo a phase called the exoerythrocytic stage.
- In the liver, sporozoites multiply asexually and transform into merozoites.

4. **Invasion of Red Blood Cells (RBCs)**:
- Merozoites are released from the liver and enter the RBCs, where they continue to multiply through a process known as erythrocytic schizogony.

5. **Symptoms of Malaria**:
- The clinical symptoms of malaria, such as fever and chills, appear when the merozoites burst out of the RBCs, causing the release of toxins and leading to the characteristic fever.

6. **Timing of Detection in RBCs**:
- Malarial parasites can be detected in the RBCs of a patient when the temperature rises with rigor (during fever). This is when the merozoites are actively present in the RBCs.

7. **Conclusion**:
- Therefore, the correct statement is that the malarial parasite can be obtained in the RBCs of a patient when the temperature rises with rigor, indicating the presence of the parasite during the symptomatic phase of malaria.