Which of the following antibody is related to allergic response?

Options

A. a.IgA
B. b.IgD
C. c.IgE
D. d.IgG

Answer

**Step-by-Step Solution:**

1. **Understanding Antibodies**: Antibodies, also known as immunoglobulins, are proteins produced by the immune system to identify and neutralize foreign objects like bacteria and viruses. There are several classes of antibodies, each with specific functions.

2. **Identifying the Options**: The question provides four options:
- Immunoglobulin A (IgA)
- Immunoglobulin D (IgD)
- Immunoglobulin E (IgE)
- Immunoglobulin G (IgG)

3. **Function of Each Antibody**:
- **IgA**: Primarily found in mucosal areas, such as the gut, respiratory tract, and urogenital tract, and plays a crucial role in mucosal immunity.
- **IgD**: Functions mainly as a receptor on B cells that have not been exposed to antigens; its exact role is less understood.
- **IgE**: This antibody is specifically associated with allergic reactions and responses to parasitic infections. It binds to allergens and triggers histamine release from mast cells and basophils, leading to allergic symptoms.
- **IgG**: The most abundant antibody in the blood and extracellular fluid, it plays a key role in the immune response and can neutralize toxins and pathogens.

4. **Conclusion**: Based on the functions of the antibodies, IgE is the one that is directly related to allergic responses. It is responsible for the body's reaction to allergens.

5. **Final Answer**: Therefore, the antibody that is related to allergic response is **Immunoglobulin E (IgE)**.

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