Which of the following is incorrect with respect to HIV infection?

Options

A. HIV/AIDS is not spread by mere touch or physical contact, it speads only through body fluids.
B. Macrophages continue to produce virus and, in this way, act like an HIV factor
C. HIV enters into the helper T-lymphocytes `(T_(H)),` replicates, and produces progeny virus which leads to a progressive decrease in the number of helper T-lymphocytes in the body of infected person.
D. HIV does not get transmitted through organ transplant from an HIV infected person.

Answer

To determine which statement is incorrect with respect to HIV infection, we will analyze each of the provided statements one by one.

### Step 1: Analyze the First Statement
**Statement:** "HIV or AIDS is not spread by mere touch or physical contact; it spreads only through body fluids."

**Analysis:** This statement is correct. HIV is transmitted through specific body fluids such as blood, semen, vaginal fluids, and breast milk. It is not spread through casual contact or touching.

### Step 2: Analyze the Second Statement
**Statement:** "Macrophages continue to produce virus; in this way, they act like an HIV factory."

**Analysis:** This statement is incorrect. While macrophages can harbor the virus and help it remain in the body, they do not produce the virus. Macrophages are immune cells that typically help in fighting infections, but they do not replicate or produce HIV.

### Step 3: Analyze the Third Statement
**Statement:** "HIV enters into the helper T-cells or helper T-lymphocytes, replicates, and produces progeny virus which leads to a progressive decrease in the number of helper T-lymphocytes in the body of an infected person."

**Analysis:** This statement is correct. HIV specifically targets helper T-cells, integrates into their DNA, and replicates, which ultimately leads to a decrease in the number of these crucial immune cells.

### Step 4: Analyze the Fourth Statement
**Statement:** "HIV does not get transmitted through organ transplant from an HIV infected person."

**Analysis:** This statement is also correct. While there is a risk of transmission through organ transplants, rigorous screening and testing have made it very unlikely for HIV to be transmitted this way.

### Conclusion
After analyzing all statements, the incorrect statement is the second one: "Macrophages continue to produce virus; in this way, they act like an HIV factory."

### Final Answer
The incorrect statement with respect to HIV infection is the second statement.

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