Cirrhosis of liver is caused by the chronic intake of

Options

A. Tobacco (Chewing)
B. Cocaine
C. Opium
D. Alcohol

Answer

### Step-by-Step Solution:

1. **Understanding Cirrhosis of the Liver**:
- Cirrhosis is a severe liver disease characterized by the replacement of healthy liver tissue with scar tissue. This process impairs liver function and can lead to serious health complications.

2. **Identifying Causes of Cirrhosis**:
- Cirrhosis can be caused by various factors, including chronic viral infections, fatty liver disease, and substance abuse.

3. **Analyzing the Given Options**:
- Option A: Tobacco chewing - While tobacco use can lead to various health issues, it is not directly linked to cirrhosis.
- Option B: Cocaine - Cocaine can have harmful effects on the body, but it is not a primary cause of cirrhosis.
- Option C: Opium - Similar to cocaine, opium is not a common cause of cirrhosis.
- Option D: Alcohol - Chronic consumption of alcohol is a well-known cause of liver damage and cirrhosis.

4. **Conclusion**:
- Based on the analysis, the chronic intake of alcohol is the primary cause of cirrhosis of the liver. Therefore, the correct answer is **Option D: Alcohol**.