All the following statements about Stanley Cohen and Herbert Boyer are correct but one is wrong. Which one is wrong

Options

A. They discovered recombinant DNA (rDNA) technology, and this marks the birth of modern biotechnology.
B. They first produced healthy sheep clone, a Finn Dorset lamb, Dolly, from the differentiated adult mammary cells.
C. They invented genetic engineering by combining a piece of foreign DNA containing a gene from a bacterium with a bacterial plasmid using the enzyme restriction endonuclease.
D. They isolated the antibiotic resistance gene by cutting out a piece of DNA from the pasmid which was responsible for conferring antibiotic resistance.

Answer

To determine which statement about Stanley Cohen and Herbert Boyer is incorrect, we will analyze each statement one by one.

### Step-by-Step Solution:

1. **Understanding the Contributions of Cohen and Boyer**:
- Stanley Cohen and Herbert Boyer are known as the pioneers of recombinant DNA technology. They played a crucial role in the development of genetic engineering.

2. **Evaluating the Statements**:
- **Statement 1**: They discovered recombinant DNA technology, marking the birth of modern biotechnology.
- This statement is correct. Cohen and Boyer are indeed credited with the discovery of recombinant DNA technology.

- **Statement 2**: They first produced the healthy sheep clone, Dolly, from differentiated adult mammary cells.
- This statement is incorrect. The cloning of Dolly the sheep was performed by Keith Campbell and Ian Wilmut, not Cohen and Boyer. Therefore, this is the wrong statement.

- **Statement 3**: They invented genetic engineering by combining a piece of foreign DNA with a bacterial plasmid using restriction endonuclease.
- This statement is correct. Cohen and Boyer did invent genetic engineering techniques that involved the use of plasmids and restriction enzymes.

- **Statement 4**: They isolated the antibiotic resistance gene by cutting out a piece of DNA from the plasmid responsible for conferring antibiotic resistance.
- This statement is also correct. They successfully isolated antibiotic resistance genes using their techniques.

3. **Conclusion**:
- The only incorrect statement among the options provided is Statement 2, which attributes the cloning of Dolly to Cohen and Boyer instead of the actual scientists involved.

### Final Answer:
The wrong statement is: "They first produced the healthy sheep clone, Dolly, from differentiated adult mammary cells."