`alpha-D-`glucose and `beta-D-`glucose are enantiomers. True/False

Answer

To determine whether alpha-D-glucose and beta-D-glucose are enantiomers, we need to analyze their structures and the definitions of enantiomers and anomers.

### Step-by-Step Solution:

1. **Understanding Enantiomers**:
- Enantiomers are a type of stereoisomer that are non-superimposable mirror images of each other. They must have at least one chiral center and differ in configuration at all chiral centers.

2. **Identifying the Structures**:
- Alpha-D-glucose and beta-D-glucose are both cyclic forms of glucose. They differ in the configuration of the hydroxyl group (-OH) attached to the anomeric carbon (the first carbon in the cyclic structure).

3. **Analyzing the Anomeric Carbon**:
- In alpha-D-glucose, the -OH group on the anomeric carbon (C1) is on the opposite side (trans) of the CH2OH group (C6).
- In beta-D-glucose, the -OH group on the anomeric carbon (C1) is on the same side (cis) as the CH2OH group (C6).

4. **Conclusion on their Relationship**:
- Since alpha-D-glucose and beta-D-glucose differ only at the anomeric carbon and have the same configuration at all other chiral centers, they are not enantiomers. Instead, they are classified as anomers, which are a specific type of epimer that differ at the anomeric carbon.

5. **Final Answer**:
- Therefore, the statement "alpha-D-glucose and beta-D-glucose are enantiomers" is **False**.